Organic Spectroscopic Methods

2D NMR contour plot of a dehydroannulene

Course Syllabus:

• Syllabus

Course Structure:

• Introduction
• IR and Raman Spectroscopy
• History of Nuclear Magnetic Resonance (NMR)
• NMR – The Chemical Shift
• NMR – Spin-Spin Coupling
• NMR – First Order Coupling
• NMR – Second Order Coupling
• NMR – Heteroatom Couplings
• NMR – Multiple Pulse Experiments
• NMR – 2-Dimensional Experiments (COSY, NOESY, HSQC, HMBC, ADQUATE, INADEQUATE experiments)
• NMR – Spin Gymnastics (Inversion Recovery, Spin-Lock, Carr-Purcell-Meiboom-Gill (CPMG) Experiments)
• NMR – Spin Gymnastics on Steroids (1D and 2D TOCSY, 2D HSQC-TOCSY, and 3D experiments, Attached Proton Test, DEPT)
• Mass Spectrometry
  
• X-ray Crystal Structure Analysis (taught by Dr. Duilio Cascio)

Teaching Assistant:

• Vince Hipwell
  • Problem Practice Sessions:  TBA

Problems Set Assignments:

• Each week, TBA